By absorbing Colonial Bank, BB&T Corp. is staking a claim to be the Southeast's dominant regional bank, but it will face challenges maximizing the value of the purchase.

Analysts largely expressed confidence in BB&T's ability to take on such a large bank, though it is the biggest acquisition in the company's history. BB&T is buying 346 branches, $22 billion in assets, and $20 billion in deposits. BB&T agreed to a loss-sharing agreement with the Federal Deposit Insurance Corp. on $15 billion in assets.

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