As the head of the largest woman-run hedge fund in the United States, it's easy to understand why Anne Dias Griffin has made this list for a third consecutive year.

After surviving a tumultuous 2008, which by an outside estimate saw Aragon Global Management's portfolio decline by 16 percent, Griffin has helped guide the fund back. According to Mutual Fund Facts About Individual Stocks (MFFAIS) the Chicago-based portfolio has increased 2.5 percent to a current hypothetical value of $68 million, which is based on the SEC 13F-HR as of Aug. 14, over the previous 100 days.

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