The carnage in the mortgage banking business intensified on Wednesday as Resource Bancshares Mortgage Group and Bank of America Corp. disclosed big cuts in their home-lending staffs.

Resource, of Columbia, S.C., said it would cut its workforce by 18%, or 242 people, joining a long list of home lenders that have fired employees as interest rates rose this year. The lender said most of the cuts would be in production-support jobs like underwriting, closing, and processing, and in administrative functions like legal and accounting.

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